SLU-PP-332

SLU-PP-332

Common Name SLU-PP-332
CAS Number 303760-60-3
Molecular Weight 290.32
Density N/A
Boiling Point N/A
Molecular Formula C18H14N2O2
Melting Point N/A
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Product Introduction

Names

NameSLU-PP-332

SLU-PP-332 Biological Activity

DescriptionSLU-PP-332 is a pan-Estrogen Receptor/ERR agonist with EC50 values of 98, 230 and 430 nM for ERRα, ERRβ and ERRγ, respectively. SLUPP-332 enhances mitochondrial function and cellular respiration in skeletal muscle cell lines. SLU-PP-332 has the potential to study metabolic diseases as well as improve muscle function[1].
Related CatalogSignaling Pathways >> Others >> Estrogen Receptor/ERRResearch Areas >> Metabolic Disease
Target

ERRα:98 nM (EC50)

ERRβ:230 nM (EC50)

ERRγ:430 nM (EC50)

References

[1]. Billon C, et al. Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity. ACS Chem Biol. 2023 Apr 21;18(4):756-771. 

Chemical & Physical Properties

Molecular FormulaC18H14N2O2
Molecular Weight290.32
InChIKeyRNZIMBFHRXYRLL-XDHOZWIPSA-N
SMILESO=C(NN=Cc1ccc2ccccc2c1)c1ccc(O)cc1


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